| EC |
4.2.1.103 |
| Accepted name: |
cyclohexyl-isocyanide hydratase |
| Reaction: |
N-cyclohexylformamide = cyclohexyl isocyanide + H2O |
| Other name(s): |
isonitrile hydratase; N-cyclohexylformamide hydro-lyase |
| Systematic name: |
N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming) |
| Comments: |
The enzyme from Pseudomonas putida strain N19-2 can also catalyse the hydration of other isonitriles to the corresponding N-substituted formamides. The enzyme has no metal requirements. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 358974-06-8 |
| References: |
| 1. |
Goda, M., Hashimoto, Y., Shimizu, S. and Kobayashi, M. Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage. J. Biol. Chem. 276 (2001) 23480–23485. [DOI] [PMID: 11306561] |
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| [EC 4.2.1.103 created 2001] |
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