| EC |
4.1.3.22 |
| Accepted name: |
citramalate lyase |
| Reaction: |
(2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate |
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For diagram of reaction, click here |
| Glossary: |
(+)-citramalate = (2S)-2-hydroxy-2-methylbutanedioate |
| Other name(s): |
citramalate pyruvate-lyase; citramalate synthase; citramalic-condensing enzyme; citramalate synthetase; citramalic synthase; (S)-citramalate lyase; (+)-citramalate pyruvate-lyase; citramalate pyruvate lyase; (3S)-citramalate pyruvate-lyase; (2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase |
| Systematic name: |
(2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase (acetate-forming) |
| Comments: |
The enzyme can be dissociated into components, two of which are identical with EC 2.8.3.11 (citramalate CoA-transferase) and EC 4.1.3.25 (citramalyl-CoA lyase). |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9027-93-4 |
| References: |
| 1. |
Barker, H.A. Citramalate lyase of Clostridium tetanomorphum. Arch. Mikrobiol. 59 (1967) 4–12. [PMID: 4301387] |
| 2. |
Dimroth, P., Buckel, W., Loyal, R. and Eggerer, H. Isolation and function of the subunits of citramalate lyase and formation of hybrids with the subunits of citrate lyase. Eur. J. Biochem. 80 (1977) 469–477. [DOI] [PMID: 923590] |
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| [EC 4.1.3.22 created 1972] |
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