| EC |
4.1.2.11 |
| Accepted name: |
hydroxymandelonitrile lyase |
| Reaction: |
(S)-4-hydroxymandelonitrile = cyanide + 4-hydroxybenzaldehyde |
| Other name(s): |
hydroxynitrile lyase; oxynitrilase; Sorghum hydroxynitrile lyase; (S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase |
| Systematic name: |
(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming) |
| Comments: |
Does not accept aliphatic hydroxynitriles, unlike EC 4.1.2.10 [(R)-mandelonitrile lyase], EC 4.1.2.46 [aliphatic (R)-hydroxynitrile lyase] and EC 4.1.2.47 [(S)-hydroxynitrile lyase]. |
| Links to other databases: |
BRENDA, EXPASY, GENE, KEGG, MetaCyc, PDB, CAS registry number: 9075-38-1 |
| References: |
| 1. |
Bové, C. and Conn, E.E. Metabolism of aromatic compounds in higher plants. II. Purification and properties of the oxynitrilase of Sorghum vulgare. J. Biol. Chem. 236 (1961) 207–210. |
| 2. |
Seely, M.K., Criddle, R.S. and Conn, E.E. The metabolism of aromatic compounds in higher plants. 8. On the requirement of hydroxynitrile lyase for flavin. J. Biol. Chem. 241 (1966) 4457–4462. [PMID: 5922969] |
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| [EC 4.1.2.11 created 1965, modified 1999] |
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