| EC |
4.1.1.95 |
| Accepted name: |
L-glutamyl-[BtrI acyl-carrier protein] decarboxylase |
| Reaction: |
L-glutamyl-[BtrI acyl-carrier protein] = 4-amino butanoyl-[BtrI acyl-carrier protein] + CO2 |
| Other name(s): |
btrK (gene name) |
| Systematic name: |
L-glutamyl-[BtrI acyl-carrier protein] carboxy-lyase |
| Comments: |
Binds pyridoxal 5′-phosphate. Catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family. Has very low activity with substrates not bound to an acyl-carrier protein. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Li, Y., Llewellyn, N.M., Giri, R., Huang, F. and Spencer, J.B. Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway. Chem. Biol. 12 (2005) 665–675. [DOI] [PMID: 15975512] |
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| [EC 4.1.1.95 created 2012] |
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