| EC |
4.1.1.4 |
| Accepted name: |
acetoacetate decarboxylase |
| Reaction: |
acetoacetate + H+ = acetone + CO2 |
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For diagram of mevalonate biosynthesis, click here |
| Other name(s): |
acetoacetic acid decarboxylase; acetoacetate carboxy-lyase |
| Systematic name: |
acetoacetate carboxy-lyase (acetone-forming) |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9025-03-0 |
| References: |
| 1. |
Davies, R. Studies of the acetone-butanol fermentation. 4. Acetoacetic acid decarboxylase of Cl. acetobutylicum (BY). Biochem. J. 37 (1943) 230–238. [PMID: 16747621] |
| 2. |
Zerner, B., Coutts, S.M., Lederer, F., Waters, H.H. and Westheimer, F.H. Acetoacetate decarboxylase. Preparation of the enzyme. Biochemistry 5 (1966) 813–816. [PMID: 5911291] |
| 3. |
Ho, M.C., Menetret, J.F., Tsuruta, H. and Allen, K.N. The origin of the electrostatic perturbation in acetoacetate decarboxylase. Nature 459 (2009) 393–397. [DOI] [PMID: 19458715] |
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| [EC 4.1.1.4 created 1961] |
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