EC |
4.1.1.37 |
Accepted name: |
uroporphyrinogen decarboxylase |
Reaction: |
uroporphyrinogen III = coproporphyrinogen III + 4 CO2 |
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For diagram of the later stages of porphyrin biosynthesis, click here |
Other name(s): |
uroporphyrinogen III decarboxylase; porphyrinogen carboxy-lyase; porphyrinogen decarboxylase; uroporphyrinogen-III carboxy-lyase |
Systematic name: |
uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming) |
Comments: |
Acts on a number of porphyrinogens. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9024-70-8 |
References: |
1. |
Mauzerall, D. and Granick, S. Porphyrin biosynthesis in erythrocytes. III. Uroporphyrinogen and its decarboxylase. J. Biol. Chem. 232 (1958) 1141–1162. [PMID: 13549492] |
2. |
Tomio, J.M., Garcia, R.C., San Martin de Viale, L.C. and Grinstein, M. Porphyrin biosynthesis. VII. Porphyrinogen carboxy-lyase from avian erythrocytes. Purification and properties. Biochim. Biophys. Acta 198 (1970) 353–363. [DOI] [PMID: 4984554] |
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[EC 4.1.1.37 created 1965] |
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