| EC |
4.1.1.29 |
| Accepted name: |
sulfinoalanine decarboxylase |
| Reaction: |
3-sulfino-L-alanine = hypotaurine + CO2 |
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For diagram of taurine biosynthesis, click here |
| Other name(s): |
cysteine-sulfinate decarboxylase; L-cysteinesulfinic acid decarboxylase; cysteine-sulfinate decarboxylase; CADCase/CSADCase; CSAD; cysteic decarboxylase; cysteinesulfinic acid decarboxylase; cysteinesulfinate decarboxylase; sulfoalanine decarboxylase; 3-sulfino-L-alanine carboxy-lyase |
| Systematic name: |
3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming) |
| Comments: |
A pyridoxal-phosphate protein. Also acts on L-cysteate. The 1992 edition of the Enzyme List erroneously gave the name sulfoalanine decarboxylase to this enzyme. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 62213-10-9 |
| References: |
| 1. |
Guion-Rain, M.C., Portemer, C. and Chatagner, F. Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties. Biochim. Biophys. Acta 384 (1975) 265–276. [DOI] [PMID: 236774] |
| 2. |
Jacobsen, J.G., Thomas, L.L. and Smith, L.H., Jr. Properties and distribution of mammalian L-cysteine sulfinate carboxy-lyases. Biochim. Biophys. Acta 85 (1964) 103–116. [PMID: 14159288] |
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| [EC 4.1.1.29 created 1961, deleted 1972, reinstated 1976, modified 1983, modified 1999] |
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