The Enzyme Database

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EC 4.1.1.110     
Accepted name: bisphosphomevalonate decarboxylase
Reaction: (R)-3,5-bisphosphomevalonate = isopentenyl phosphate + CO2 + phosphate
Other name(s): mevalonate 3,5-bisphosphate decarboxylase
Systematic name: (R)-3,5-bisphosphomevalonate carboxy-lyase (isopentenyl-phosphate-forming)
Comments: The enzyme participates in an alternative mevalonate pathway that takes place in extreme acidophiles of the Thermoplasmatales order. cf. EC 4.1.1.99, phosphomevalonate decarboxylase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Vinokur, J.M., Cummins, M.C., Korman, T.P. and Bowie, J.U. An adaptation to life in acid through a novel mevalonate pathway. Sci. Rep. 6 (2016) 39737. [DOI] [PMID: 28004831]
[EC 4.1.1.110 created 2018]
 
 


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