| EC |
4.1.1.1 |
| Accepted name: |
pyruvate decarboxylase |
| Reaction: |
a 2-oxo carboxylate = an aldehyde + CO2 |
| Glossary: |
thiamine diphosphate = 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-diphosphoethyl)-4-methyl-1,3-thiazolium |
| Other name(s): |
α-carboxylase (ambiguous); pyruvic decarboxylase; α-ketoacid carboxylase; 2-oxo-acid carboxy-lyase |
| Systematic name: |
2-oxo-acid carboxy-lyase (aldehyde-forming) |
| Comments: |
A thiamine-diphosphate protein. Also catalyses acyloin formation. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9001-04-1 |
| References: |
| 1. |
Singer, T.P. and Pensky, J. Isolation and properties of the α-carboxylase of wheat germ. J. Biol. Chem. 196 (1952) 375–388. [PMID: 12980978] |
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| [EC 4.1.1.1 created 1961] |
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