| EC |
3.6.1.40 |
| Accepted name: |
guanosine-5′-triphosphate,3′-diphosphate phosphatase |
| Reaction: |
guanosine 5′-triphosphate 3′-diphosphate + H2O = guanosine 3′,5′-bis(diphosphate) + phosphate |
| Other name(s): |
pppGpp 5′-phosphohydrolase; guanosine 5′-triphosphate-3′-diphosphate 5′-phosphohydrolase; guanosine pentaphosphatase; guanosine pentaphosphate phosphatase; guanosine 5′-triphosphate 3′-diphosphate 5′-phosphatase; guanosine pentaphosphate phosphohydrolase |
| Systematic name: |
guanosine-5′-triphosphate-3′-diphosphate 5′-phosphohydrolase |
| Comments: |
Also hydrolyses other guanosine 5′-triphosphate derivatives with at least one unsubstituted phosphate group on the 3′-position, but not GTP, ATP or adenosine 5′-triphosphate 3′-diphosphate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 85130-44-5 |
| References: |
| 1. |
Hara, A. and Sy, J. Guanosine 5′-triphosphate, 3′-diphosphate 5′-phosphohydrolase. Purification and substrate specificity. J. Biol. Chem. 258 (1983) 1678–1683. [PMID: 6130093] |
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| [EC 3.6.1.40 created 1986, modified 2010] |
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