| EC |
3.6.1.18 |
| Accepted name: |
FAD diphosphatase |
| Reaction: |
FAD + H2O = AMP + FMN |
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For diagram of FAD biosynthesis, click here |
| Other name(s): |
FAD pyrophosphatase; riboflavin adenine dinucleotide pyrophosphatase; flavin adenine dinucleotide pyrophosphatase; riboflavine adenine dinucleotide pyrophosphatase; flavine adenine dinucleotide pyrophosphatase |
| Systematic name: |
FAD nucleotidohydrolase |
| Comments: |
The plant enzyme also hydrolyses NAD+ and NADH; the animal enzyme hydrolyses NAD+ and CoA at about half of the rate of hydrolysis of FAD. May be identical with EC 3.6.1.9 nucleotide diphosphatase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37289-30-8 |
| References: |
| 1. |
Ravindranath, S.D. and Appaji Rao, N. Nucleotidases in plants. 3. Effect of metabolites on the enzyme hydrolyzing flavine adenine dinucleotide (FAD) from Phaseolus radiatus. Arch. Biochem. Biophys. 133 (1969) 54–59. [DOI] [PMID: 5810832] |
| 2. |
Shin, H.J. and Mego, J.L. A rat liver lysosomal membrane flavin-adenine dinucleotide phosphohydrolase: purification and characterization. Arch. Biochem. Biophys. 267 (1988) 95–103. [DOI] [PMID: 2848456] |
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| [EC 3.6.1.18 created 1972] |
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