EC |
3.5.4.35 |
Accepted name: |
tRNA(cytosine8) deaminase |
Reaction: |
cytosine8 in tRNA + H2O = uracil8 in tRNA + NH3 |
Other name(s): |
CDAT8 |
Systematic name: |
tRNA(cytosine8) aminohydrolase |
Comments: |
The enzyme from Methanopyrus kandleri specifically catalyses the deamination of cytosine at position 8 of tRNA in 30 different tRNAs. This cytosine-to-uracil editing guarantees the proper folding and functionality of the tRNAs. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
References: |
1. |
Randau, L., Stanley, B.J., Kohlway, A., Mechta, S., Xiong, Y. and Söll, D. A cytidine deaminase edits C to U in transfer RNAs in Archaea. Science 324 (2009) 657–659. [DOI] [PMID: 19407206] |
|
[EC 3.5.4.35 created 2013] |
|
|
|
|