The Enzyme Database

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Accepted name: IMP cyclohydrolase
Reaction: IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
For diagram of purine biosynthesis (late stages), click here
Other name(s): inosinicase; inosinate cyclohydrolase; IMP 1,2-hydrolase (decyclizing)
Systematic name: IMP 1,2-hydrolase (ring-opening)
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9013-81-4
1.  Flaks, J.G., Erwin, M.J. and Buchanan, J.M. Biosynthesis of the purines. XVIII. 5-Amino-1-ribosyl-4-imidazolecarboxamide 5′-phosphate transformylase and inosinicase. J. Biol. Chem. 229 (1957) 603–612. [PMID: 13502325]
[EC created 1961, modified 2000]

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