| EC |
3.5.3.12 |
| Accepted name: |
agmatine deiminase |
| Reaction: |
agmatine + H2O = N-carbamoylputrescine + NH3 |
| Glossary: |
agmatine = (4-aminobutyl)guanidine |
| Other name(s): |
agmatine amidinohydrolase |
| Systematic name: |
agmatine iminohydrolase |
| Comments: |
The plant enzyme also catalyses the reactions of EC 2.1.3.3 (ornithine carbamoyltransferase), EC 2.1.3.6 (putrescine carbamoyltransferase) and EC 2.7.2.2 (carbamate kinase), thus functioning as a putrescine synthase, converting agmatine and ornithine into putrescine and citrulline, respectively. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37289-17-1 |
| References: |
| 1. |
Smith, T.A. Agmatine iminohydrolase in maize. Phytochemistry 8 (1969) 2111–2117. |
| 2. |
Srivenugopal, K.S. and Adiga, P.R. Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase). J. Biol. Chem. 256 (1981) 9532–9541. [PMID: 6895223] |
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| [EC 3.5.3.12 created 1972] |
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