| EC |
3.5.2.3 |
| Accepted name: |
dihydroorotase |
| Reaction: |
(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate |
|
For diagram of pyrimidine biosynthesis, click here |
| Other name(s): |
carbamoylaspartic dehydrase; dihydroorotate hydrolase |
| Systematic name: |
(S)-dihydroorotate amidohydrolase |
| Links to other databases: |
BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9024-93-5 |
| References: |
| 1. |
Cooper, C. and Wilson, D.W. Biosynthesis of pyrimidines. Fed. Proc. 13 (1954) 194. |
| 2. |
Lieberman, I. and Kornberg, A. Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. II. Dihydroorotic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin. J. Biol. Chem. 207 (1954) 911–924. [PMID: 13163076] |
|
| [EC 3.5.2.3 created 1961] |
| |
|
| |
|
Printable version