ExplorEnz: EC 3.5.2.11

3.5.2.11

Accepted name:

L-lysine-lactamase

Reaction:

(S)-2-aminohexano-6-lactam + H₂O = L-lysine

Glossary:

(S)-2-aminohexano-6-lactam = L-lysine 1,6-lactam

Other name(s):

L-α-aminocaprolactam hydrolase; L-lysinamidase; L-lysine-1,6-lactam lactamhydrolase

Systematic name:

(S)-2-aminohexano-6-lactam lactamhydrolase

Comments:

Also hydrolyses L-lysinamide.

References:

1.	Fukumura, T., Talbot, G., Misono, H., Teremura, Y., Kato, K. and Soda, K. Purification and properties of a novel enzyme, L- α-amino-ε-caprolactamase from Cryptococcus laurentii. FEBS Lett. 89 (1978) 298–300. [PMID: 26602]
2.	Shvyadas, V.K., Galaev, I.Yu. and Kozlova, E.V. Preparation and characterization of L-α-aminocaprolactam hydrolase from cells of Cryptococcus laurentii. Biochemistry (Moscow) 49 (1984) 1268–1273.

[EC 3.5.2.11 created 1981, modified 1989]