EC |
3.5.1.76 |
Accepted name: |
arylalkyl acylamidase |
Reaction: |
N-acetylarylalkylamine + H2O = arylalkylamine + acetate |
Other name(s): |
aralkyl acylamidase |
Systematic name: |
N-acetylarylalkylamine amidohydrolase |
Comments: |
Identified in Pseudomonas putida. Strict specificity for N-acetyl arylalkylamines, including N-acetyl-2-phenylethylamine, N-acetyl-3-phenylpropylamine, N-acetyldopamine, N-acetyl-serotonin and melatonin. It also accepts arylalkyl acetates but not acetanilide derivatives, which are common substrates of EC 3.5.1.13, aryl acylamidase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Shimizu, S., Ogawa, J., Chung, M.C.-M., Yamada, H. Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2. Eur. J. Biochem. 209 (1992) 375–382. [DOI] [PMID: 1396711] |
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[EC 3.5.1.76 created 1999] |
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