The Enzyme Database

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EC 3.5.1.130     
Accepted name: [amino group carrier protein]-lysine hydrolase
Reaction: [amino group carrier protein]-C-terminal-γ-(L-lysyl)-L-glutamate + H2O = [amino group carrier protein]-C-terminal-L-glutamate + L-lysine
Other name(s): lysK (gene name)
Systematic name: [amino group carrier protein]-C-terminal-γ-L-lysyl-L-glutamate amidohydrolase
Comments: The enzyme participates in an L-lysine biosynthetic pathways in certain species of archaea and bacteria. In some organisms the enzyme also catalyses the activity of EC 3.5.1.132, [amino group carrier protein]-ornithine hydrolase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Horie, A., Tomita, T., Saiki, A., Kono, H., Taka, H., Mineki, R., Fujimura, T., Nishiyama, C., Kuzuyama, T. and Nishiyama, M. Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus. Nat. Chem. Biol. 5 (2009) 673–679. [DOI] [PMID: 19620981]
[EC 3.5.1.130 created 2019]
 
 


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