| EC |
3.5.1.116 |
| Accepted name: |
ureidoglycolate amidohydrolase |
| Reaction: |
(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2 |
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For diagram of AMP catabolism, click here |
| Other name(s): |
ureidoglycolate hydrolase; UAH (gene name) |
| Systematic name: |
(S)-ureidoglycolate amidohydrolase (decarboxylating) |
| Comments: |
This plant enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 4.3.2.3, ureidoglycolate lyase, which releases urea rather than ammonia. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 115629-07-7 |
| References: |
| 1. |
Winkler, R.G., Blevins, D.G. and Randall, D.D. Ureide catabolism in soybeans. III. Ureidoglycolate amidohydrolase and allantoate amidohydrolase are activities of an allantoate degrading enzyme complex. Plant Physiol. 86 (1988) 1084–1088. [PMID: 16666035] |
| 2. |
Wells, X.E. and Lees, E.M. Ureidoglycolate amidohydrolase from developing French bean fruits (Phaseolus vulgaris [L.].). Arch. Biochem. Biophys. 287 (1991) 151–159. [DOI] [PMID: 1910298] |
| 3. |
Werner, A.K., Romeis, T. and Witte, C.P. Ureide catabolism in Arabidopsis thaliana and Escherichia coli. Nat. Chem. Biol. 6 (2010) 19–21. [DOI] [PMID: 19935661] |
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| [EC 3.5.1.116 created 1992 as EC 3.5.3.19, transferred 2014 to EC 3.5.1.116] |
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