The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: peptidyl-Asp metalloendopeptidase
Reaction: Cleavage of Xaa┼Asp, Xaa┼Glu and Xaa┼cysteic acid bonds
Other name(s): endoproteinase Asp-N; peptidyl-Asp metalloproteinase
Comments: A metalloenzyme isolated from Pseudomonas fragi. Useful in protein sequencing applications because of its limited specificity. In peptidase family M72.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 55576-49-3
1.  Porzio, M.A. and Pearson, A.M. Isolation of an extracellular neutral proteinase from Pseudomonas fragi. Biochim. Biophys. Acta 384 (1975) 235–241. [DOI] [PMID: 236771]
2.  Drapeau, G.R. Substrate specificity of a proteolytic enzyme isolated from a mutant of Pseudomonas fragi. J. Biol. Chem. 255 (1980) 839–840. [PMID: 7188696]
3.  Ingrosso, D., Fowler, A.V., Bleibaum, J. and Clarke, S. Specificity of endoproteinase Asp-N (Pseudomonas fragi): cleavage at glutamyl residues in two proteins. Biochem. Biophys. Res. Commun. 162 (1989) 1528–1534. [DOI] [PMID: 2669754]
[EC created 1992]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald