The Enzyme Database

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Accepted name: thermopsin
Reaction: Similar in specificity to pepsin A preferring bulky hydrophobic amino acids in P1 and P1′
Comments: From the thermophilic archaeon Sulfolobus acidocaldarius. Maximally active at pH 2 and 90 °C. Weakly inhibited by pepstatin but shows no sequence similarity to pepsin. Type example of peptidase family A5.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, MEROPS, CAS registry number: 126125-05-1
1.  Lin, X. and Tang, J. Thermopsin. Methods Enzymol. 248 (1995) 156–168. [PMID: 7674919]
[EC created 1992 as EC, transferred 2000 to EC]

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