EC |
3.4.22.31 |
Accepted name: |
ananain |
Reaction: |
Hydrolysis of proteins with broad specificity for peptide bonds. Best reported small molecule substrate Bz-Phe-Val-Arg┼NHMec, but broader specificity than fruit bromelain |
Other name(s): |
stem bromelain; fruit bromelain |
Comments: |
From stem of pineapple plant, Ananas comosus. Differs from stem and fruit bromelains in being inhibited by chicken cystatin. In peptidase family C1 (papain family) |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, MEROPS, PDB, CAS registry number: 119129-70-3 |
References: |
1. |
Rowan, A.D., Buttle, D.J. and Barrett, A.J. Ananain: a novel cysteine proteinase found in pineapple stem. Arch. Biochem. Biophys. 267 (1988) 262–270. [DOI] [PMID: 3196029] |
2. |
Rowan, A.D., Buttle, D.J. and Barrett, A.J. The cysteine proteinases of the pineapple plant. Biochem. J. 266 (1990) 869–875. [PMID: 2327970] |
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[EC 3.4.22.31 created 1992] |
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