The Enzyme Database

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Accepted name: 3α(S)-strictosidine β-glucosidase
Reaction: strictosidine + H2O = D-glucose + strictosidine aglycone
For diagram of geissoschizine and sarpagine biosynthesis, click here
Systematic name: strictosidine β-D-glucohydrolase
Comments: Does not act on a number of closely related glycosides. Strictosidine is a precursor of indole alkaloids.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 73379-57-4
1.  Hemscheidt, T. and Zenk, M.H. Glucosidases involved in indole alkaloid biosynthesis of Catharanthus cell cultures. FEBS Lett. 110 (1980) 187–191. [DOI] [PMID: 6768587]
2.  Barleben, L., Ma, X., Koepke, J., Peng, G., Michel, H. and Stöckigt, J. Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Biochim. Biophys. Acta 1747 (2005) 89–92. [DOI] [PMID: 15680242]
[EC created 1984]

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