| EC |
3.2.1.103 |
| Accepted name: |
keratan-sulfate endo-1,4-β-galactosidase |
| Reaction: |
Endohydrolysis of (1→4)-β-D-galactosidic linkages in keratan sulfate |
| Other name(s): |
endo-β-galactosidase (ambiguous); keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase |
| Systematic name: |
keratan-sulfate 4-β-D-galactanohydrolase |
| Comments: |
Hydrolyses the 1,4-β-D-galactosyl linkages adjacent to 1,3-N-acetyl-α-D-glucosaminyl residues. Also acts on some non-sulfated oligosaccharides, but only acts on blood group substances when the 1,2-linked fucosyl residues have been removed (cf. EC 3.2.1.102 blood-group-substance endo-1,4-β-galactosidase). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 55072-01-0 |
| References: |
| 1. |
Fukuda, M.N. and Matsumara, G. Endo-β-galactosidase of Escherichia freundii. Purification and endoglycosidic action on keratan sulfates, oligosaccharides, and blood group active glycoprotein. J. Biol. Chem. 251 (1976) 6218–6225. [PMID: 135762] |
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| [EC 3.2.1.103 created 1984] |
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