ExplorEnz: EC 3.13.1.7

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3.13.1.7

Accepted name:

carbonyl sulfide hydrolase

Reaction:

carbonyl sulfide + H₂O = hydrogen sulfide + CO₂

Other name(s):

COSase; COS hydrolase; cos (gene name)

Systematic name:

carbonyl sulfide hydrogen-sulfide-lyase (decarboxylating)

Comments:

The enzyme, characterized from the bacterium Thiobacillus thioparus, catalyses a step in the degradation pathway of thiocyanate. This activity is also catalysed by the archaeal EC 3.13.1.5, carbon disulfide lyase.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB

References:

Ogawa, T., Noguchi, K., Saito, M., Nagahata, Y., Kato, H., Ohtaki, A., Nakayama, H., Dohmae, N., Matsushita, Y., Odaka, M., Yohda, M., Nyunoya, H. and Katayama, Y. Carbonyl sulfide hydrolase from Thiobacillus thioparus strain THI115 is one of the β-carbonic anhydrase family enzymes. J. Am. Chem. Soc. 135 (2013) 3818–3825. [DOI] [PMID: 23406161]

[EC 3.13.1.7 created 2018]