| EC |
3.1.3.29 |
| Accepted name: |
N-acylneuraminate-9-phosphatase |
| Reaction: |
N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate |
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For diagram of N-Acetylneuraminic acid biosynthesis, click here |
| Other name(s): |
acylneuraminate 9-phosphatase; N-acylneuraminic acid 9-phosphate phosphatase; N-acylneuraminic (sialic) acid 9-phosphatase |
| Systematic name: |
N-acylneuraminate-9-phosphate phosphohydrolase |
| Comments: |
The enzyme, found in vertebrates, is equally active with N-acetylneuraminate 9-phosphate and N-glycoloylneuraminate 9-phosphate. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37288-13-4 |
| References: |
| 1. |
Jourdian, G.W., Swanson, A.L., Watson, D., and Roseman S. Isolation of sialic acid 9-phosphatase from human erythrocytes. J. Biol. Chem. 239 (1964) PC2714–PC2716. [DOI] [PMID: 14235556] |
| 2. |
Jourdian, G.W., Swanson, A., Watson, D. and Roseman, S. N-Acylneuraminic (sialic) acid 9-phosphatase. Methods Enzymol. 8 (1966) 205–208. [DOI] |
| 3. |
Maliekal, P., Vertommen, D., Delpierre, G. and Van Schaftingen, E. Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase. Glycobiology 16 (2006) 165–172. [DOI] [PMID: 16237198] |
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| [EC 3.1.3.29 created 1972] |
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