| EC |
3.1.3.111 |
| Accepted name: |
decaprenylphosphoryl-5-phosphoribose phosphatase |
| Reaction: |
trans,octacis-decaprenylphospho-β-D-ribofuranose 5-phosphate + H2O = trans,octacis-decaprenylphospho-β-D-ribofuranose + phosphate |
| Other name(s): |
Rv3807c (gene name) |
| Systematic name: |
trans,octacis-decaprenylphospho-β-D-ribofuranose 5-phosphate phosphohydrolase |
| Comments: |
The enzyme, studied from mycobacteria, in involved in the biosynthesis of trans,octacis-decaprenylphospho-β-D-arabinofuranose, which serves in those organisms as the arabinofuranose donor for the biosynthesis of the cell wall polymers arabinogalactan and lipoarabinomannan. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Wolucka, B.A. Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy. FEBS J. 275 (2008) 2691–2711. [DOI] [PMID: 18422659] |
| 2. |
Jiang, T., Cai, L., Zhao, X., He, L., Ma, Y., Zang, S., Zhang, C., Li, X. and Xin, Y. Functional identification of MSMEG_6402 protein from Mycobacterium smegmatis in decaprenylphosphoryl-D-arabinose biosynthesis. Microb Pathog 76 (2014) 44–50. [DOI] [PMID: 25223716] |
|
| [EC 3.1.3.111 created 2024] |
| |
|
| |
|
Printable version