| EC |
3.1.3.103 |
| Accepted name: |
3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase |
| Reaction: |
3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + H2O = 3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate + phosphate |
| Other name(s): |
3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate-9-phosphate phosphatase |
| Systematic name: |
3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphohydrolase |
| Comments: |
The enzyme, characterized from the bacterium Bacteroides thetaiotaomicron, is part of the biosynthesis pathway of the sialic acid 3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate (Kdn). Kdn is abundant in extracellular glycoconjugates of lower vertebrates such as fish and amphibians, but is also found in the capsular polysaccharides of bacteria that belong to the Bacteroides genus. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Wang, L., Lu, Z., Allen, K.N., Mariano, P.S. and Dunaway-Mariano, D. Human symbiont Bacteroides thetaiotaomicron synthesizes 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Chem. Biol. 15 (2008) 893–897. [DOI] [PMID: 18804026] |
| 2. |
Lu, Z., Wang, L., Dunaway-Mariano, D. and Allen, K.N. Structure-function analysis of 2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphatase defines specificity elements in type C0 haloalkanoate dehalogenase family members. J. Biol. Chem. 284 (2009) 1224–1233. [DOI] [PMID: 18986982] |
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| [EC 3.1.3.103 created 2016] |
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