The Enzyme Database

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Accepted name: deoxyribonuclease X
Reaction: Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes
Other name(s): Escherichia coli endodeoxyribonuclease; Escherichia coli endodeoxyribonuclease X
Comments: Preference for supercoiled DNA; little activity on linear double-stranded DNA. Inhibited by single-stranded DNA, ATP and AMP.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 97002-82-9
1.  Ghosh, S. and DasGupta, U. Studies with endonuclease X: a new deoxyendonuclease of E. coli that preferentially cleaves supercoiled plasmid DNA. Curr. Trends Life Sci. 12 (1984) 79–88.
[EC created 1992]

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