The Enzyme Database

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Accepted name: phospholipase A1
Reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate
Systematic name: phosphatidylcholine 1-acylhydrolase
Comments: This enzyme has a much broader specificity than EC phospholipase A2. Requires Ca2+.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9043-29-2
1.  Gatt, S. Purification and properties of phospholipase A-1 from rat and calf brain. Biochim. Biophys. Acta 159 (1968) 304–316. [DOI] [PMID: 5657461]
2.  Scandella, C.J. and Kornberg, A. A membrane-bound phospholipase A1 purified from Escherichia coli. Biochemistry 10 (1971) 4447–4456. [PMID: 4946924]
3.  van den Bosch, H. Intracellular phospholipases A. Biochim. Biophys. Acta 604 (1980) 191–246. [DOI] [PMID: 6252969]
4.  van den Bosch, H., Aarsman, A.J. and van Deenen, L.L.M. Isolation and properties of a phospholipase A1 activity from beef pancreas. Biochim. Biophys. Acta 348 (1974) 197–209. [DOI] [PMID: 4858811]
[EC created 1972, modified 1976]

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