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Your query returned 1 entry. Printable version
EC | 3.1.1.118 | ||||
Accepted name: | phospholipid sn-1 acylhydrolase | ||||
Reaction: | (1) a 1-phosphatidyl-1D-myo-inositol + H2O = a 2-acyl-sn-glycero-3-phospho-1D-myo-inositol + a fatty acid (2) a 1,2-diacyl-sn-glycerol 3-phosphate + H2O = a 2-acyl-sn-glycerol 3-phosphate + a fatty acid |
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Glossary: | a 1,2-diacyl-sn-glycerol 3-phosphate = a phosphatidate | ||||
Other name(s): | phospholipase DDHD1; phosphatidic acid-preferring phospholipase A1; PA-PLA1; DDHD1 (gene name) | ||||
Systematic name: | phospholipid sn-1 acylhydrolase | ||||
Comments: | The human enzyme shows broad specificity, and has a preference for phosphatidate over other phospholipids. Unlike EC 3.1.1.32, phospholipase A1, it is also active against phosphatidylinositol. It is not active towards acyl groups linked at the sn-2 position. | ||||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc | ||||
References: |
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