| EC |
2.8.2.18 |
| Accepted name: |
cortisol sulfotransferase |
| Reaction: |
3′-phosphoadenylyl sulfate + cortisol = adenosine 3′,5′-bisphosphate + cortisol 21-sulfate |
| Glossary: |
3′-phosphoadenylyl sulfate = PAPS |
| Other name(s): |
glucocorticosteroid sulfotransferase; glucocorticoid sulfotransferase; 3′-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase |
| Systematic name: |
3′-phosphoadenylyl-sulfate:cortisol 21-sulfonotransferase |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 59782-20-6 |
| References: |
| 1. |
Singer, S.S. and Brill, B. Enzymatic sulfation of steroids. XVII. The properties of the glucocorticoid sulfotransferase activity of guinea pig liver cytosol. Biochim. Biophys. Acta 712 (1982) 590–596. [DOI] [PMID: 6957246] |
| 2. |
Singer, S.S., Giera, D., Johnson, J. and Sylvester, S. Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations. Endocrinology 98 (1976) 963–974. [DOI] [PMID: 1278101] |
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| [EC 2.8.2.18 created 1986] |
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