| EC |
2.8.2.17 |
| Accepted name: |
chondroitin 6-sulfotransferase |
| Reaction: |
3′-phosphoadenylyl sulfate + chondroitin = adenosine 3′,5′-bisphosphate + chondroitin 6′-sulfate |
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For diagram of chondroitin biosynthesis (later stages), click here |
| Glossary: |
3′-phosphoadenylyl sulfate = PAPS |
| Other name(s): |
chondroitin 6-O-sulfotransferase; 3′-phosphoadenosine 5′-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase; terminal 6-sulfotransferase; 3′-phosphoadenylyl-sulfate:chondroitin 6′-sulfotransferase |
| Systematic name: |
3′-phosphoadenylyl-sulfate:chondroitin 6′-sulfonotransferase |
| Comments: |
The sulfation is at the 6-position of N-acetylgalactosamine residues of chondroitin. Not identical with EC 2.8.2.5 chondroitin 4-sulfotransferase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 37292-93-6 |
| References: |
| 1. |
Habuchi, O. and Miyashita, N. Separation and characterization of chondroitin 6-sulfotransferase and chondroitin 4-sulfotransferase from chick embryo cartilage. Biochim. Biophys. Acta 717 (1982) 414–421. [DOI] [PMID: 6957247] |
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| [EC 2.8.2.17 created 1986] |
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