The Enzyme Database

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Accepted name: aryl sulfotransferase
Reaction: 3′-phosphoadenylyl sulfate + a phenol = adenosine 3′,5′-bisphosphate + an aryl sulfate
Glossary: dopamine = 4-(2-aminoethyl)benzene-1,2-diol
3′-phosphoadenylyl sulfate = PAPS
Other name(s): phenol sulfotransferase; sulfokinase; 1-naphthol phenol sulfotransferase; 2-naphtholsulfotransferase; 4-nitrocatechol sulfokinase; arylsulfotransferase; dopamine sulfotransferase; p-nitrophenol sulfotransferase; phenol sulfokinase; ritodrine sulfotransferase; PST; 3′-phosphoadenylyl-sulfate:phenol sulfotransferase
Systematic name: 3′-phosphoadenylyl-sulfate:phenol sulfonotransferase
Comments: A number of aromatic compounds can act as acceptors. Organic hydroxylamines are not substrates (cf. EC tyrosine-ester sulfotransferase).
Links to other databases: BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9026-09-9
1.  Romain, Y., Demassieux, S. and Carriere, S. Partial purification and characterization of two isoenzymes involved in the sulfurylation of catecholamines. Biochem. Biophys. Res. Commun. 106 (1982) 999–1005. [DOI] [PMID: 6956338]
2.  Sekura, R. and Jakoby, W.B. Phenol sulfotransferases. J. Biol. Chem. 254 (1979) 5658–5663. [PMID: 447677]
[EC created 1961, modified 1980]

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