Accepted name: pyruvate, water dikinase
Reaction: ATP + pyruvate + H2O = AMP + phosphoenolpyruvate + phosphate
Other name(s): phosphoenolpyruvate synthase; pyruvate-water dikinase (phosphorylating); PEP synthetase; phosphoenolpyruvate synthase; phoephoenolpyruvate synthetase; phosphoenolpyruvic synthase; phosphopyruvate synthetase
Systematic name: ATP:pyruvate, water phosphotransferase
Comments: A manganese protein.
1.  Berman, K.M. and Cohn, M. Phosphoenolpyruvate synthetase of Escherichia coli. Purification, some properties, and the role of divalent metal ions. J. Biol. Chem. 245 (1970) 5309–5318. [PMID: 4319237]
2.  Berman, K.M. and Cohn, M. Phosphoenolpyruvate synthetase. Partial reactions studied with adenosine triphosphate analogues and the inorganic phosphate-H218O exchange reaction. J. Biol. Chem. 245 (1970) 5319–5325. [PMID: 4319238]
3.  Cooper, R.A. and Kornberg, H.L. Net formation of phosphoenolpyruvate from pyruvate by Escherichia coli. Biochim. Biophys. Acta 104 (1965) 618–620. [PMID: 5322808]
4.  Cooper, R.A. and Kornberg, H.L. Phosphoenolpyruvate synthetase. Methods Enzymol. 13 (1969) 309–314.
[EC created 1976]