EC |
2.7.8.29 |
Accepted name: |
L-serine-phosphatidylethanolamine phosphatidyltransferase |
Reaction: |
L-1-phosphatidylethanolamine + L-serine = L-1-phosphatidylserine + ethanolamine |
Other name(s): |
phosphatidylserine synthase 2; serine-exchange enzyme II; PTDSS2 (gene name) |
Systematic name: |
L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase |
Comments: |
This mammalian enzyme catalyses an exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
References: |
1. |
Stone, S.J. and Vance, J.E. Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2. Biochem. J. 342 (1999) 57–64. [PMID: 10432300] |
2. |
Tomohiro, S., Kawaguti, A., Kawabe, Y., Kitada, S. and Kuge, O. Purification and characterization of human phosphatidylserine synthases 1 and 2. Biochem. J. 418 (2009) 421–429. [DOI] [PMID: 19014349] |
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[EC 2.7.8.29 created 2010] |
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