| EC |
2.7.2.16 |
| Accepted name: |
2-phosphoglycerate kinase |
| Reaction: |
ATP + 2-phospho-D-glycerate = ADP + 2,3-diphospho-D-glycerate |
| Other name(s): |
pgk2 (gene name) |
| Systematic name: |
ATP:2-phosphoglycerate 3-phosphotransferase |
| Comments: |
The enzyme, found in a number of methanogenic archaeal genera, is involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant. Activity is stimulated by potassium ions. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Lehmacher, A., Vogt, A.B. and Hensel, R. Biosynthesis of cyclic 2,3-diphosphoglycerate. Isolation and characterization of 2-phosphoglycerate kinase and cyclic 2,3-diphosphoglycerate synthetase from Methanothermus fervidus. FEBS Lett. 272 (1990) 94–98. [PMID: 2226838] |
| 2. |
Lehmacher, A. and Hensel, R. Cloning, sequencing and expression of the gene encoding 2-phosphoglycerate kinase from Methanothermus fervidus. Mol. Gen. Genet. 242 (1994) 163–168. [PMID: 8159166] |
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| [EC 2.7.2.16 created 2019] |
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