Accepted name: kanamycin kinase
Reaction: ATP + kanamycin = ADP + kanamycin 3′-phosphate
Glossary: kanamycin
Other name(s): neomycin-kanamycin phosphotransferase;
Systematic name: ATP:kanamycin 3′-O-phosphotransferase
Comments: Also acts on the antibiotics neomycin, paromomycin, neamine, paromamine, vistamycin and gentamicin A. An enzyme from Pseudomonas aeruginosa also acts on butirosin.
1.  Doi, O., Ogura, M., Tanaka, N. and Umezawa, H. Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginosa. Appl. Microbiol. 16 (1968) 1276–1281. [PMID: 4970990]
2.  Dolin, M.I. The Streptococcus faecalis oxidases for reduced diphosphopyridine nucleotide. III. Isolation and properties of a flavin peroxidase for reduced diphosphopyridine nucleotide. J. Biol. Chem. 225 (1957) 557–573. [PMID: 13416259]
[EC created 1976]