EC |
2.7.1.161 |
Accepted name: |
CTP-dependent riboflavin kinase |
Reaction: |
CTP + riboflavin = CDP + FMN |
Other name(s): |
Methanocaldococcus jannaschii Mj0056; Mj0056 |
Systematic name: |
CTP:riboflavin 5′-phosphotransferase |
Comments: |
This archaeal enzyme differs from EC 2.7.1.26, riboflavin kinase, in using CTP as the donor nucleotide. UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP. |
Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
References: |
1. |
Ammelburg, M., Hartmann, M.D., Djuranovic, S., Alva, V., Koretke, K.K., Martin, J., Sauer, G., Truffault, V., Zeth, K., Lupas, A.N. and Coles, M. A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels. Structure 15 (2007) 1577–1590. [DOI] [PMID: 18073108] |
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[EC 2.7.1.161 created 2008] |
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