Accepted name: diphosphate-purine nucleoside kinase
Reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide
Other name(s): pyrophosphate-purine nucleoside kinase
Systematic name: diphosphate:purine nucleoside phosphotransferase
Comments: The enzyme from the Acholeplasma class of Mollicutes catalyses the conversion of adenosine, guanosine and inosine to AMP, GMP and IMP. ATP cannot substitute for diphosphate as a substrate.
1.  Tryon, V.V., Pollack, D. Purine metabolism in Acholeplasma laidlawii B: novel PPi-dependent nucleoside kinase activity. J. Bacteriol. 159 (1984) 265–270. [PMID: 6330034]
2.  Tryon, V.V., Pollack, J.D. Distinctions in Mollicutes purine metabolism: pyrophosphate-dependent nucleoside kinase and dependence on guanylate salvage. Int. J. Systematic Bacteriol. 35 (1985) 497–501.
[EC created 1999]