EC |
2.7.1.136 |
Accepted name: |
macrolide 2′-kinase |
Reaction: |
ATP + oleandomycin = ADP + oleandomycin 2′-O-phosphate |
Systematic name: |
ATP:macrolide 2′-O-phosphotransferase |
Comments: |
Erythromycin, spiramycin and some other macrolide antibiotics can also act as acceptors. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 116036-69-2 |
References: |
1. |
O'Hara, K., Kanda, T. and Kono, M. Structure of a phosphorylated derivative of oleandomycin, obtained by reaction of oleandomycin with an extract of an erythromycin-resistant strain of Escherichia coli. J. Antibiot. 41 (1988) 823–827. [PMID: 3042731] |
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[EC 2.7.1.136 created 1992] |
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