| EC |
2.6.1.74 |
| Accepted name: |
cephalosporin-C transaminase |
| Reaction: |
(7R)-7-(5-carboxy-5-oxopentanoyl)aminocephalosporinate + D-glutamate = cephalosporin C + 2-oxoglutarate |
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For diagram of cephalosporin biosynthesis, click here |
| Glossary: |
cephalosporin C = (7R)-7-(5-carboxy-5-oxopentanamido)cephalosporanate |
| Other name(s): |
cephalosporin C aminotransferase; L-alanine:cephalosporin-C aminotransferase |
| Systematic name: |
cephalosporin-C:2-oxoglutarate aminotransferase |
| Comments: |
A number of D-amino acids, including D-alanine, D-aspartate and D-methionine can also act as amino-group donors. Although this enzyme acts on several free D-amino acids, it differs from EC 2.6.1.21, D-alanine transaminase, in that it can use cephalosporin C as an amino donor. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 122096-91-7 |
| References: |
| 1. |
Aretz, W. and Sauber, K. Novel D-amino acid transaminase. Ann. N.Y. Acad. Sci. 542 (1988) 366–370. [PMID: 3228235] |
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| [EC 2.6.1.74 created 1992, modified 2005] |
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