| EC |
2.6.1.64 |
| Accepted name: |
glutamine—phenylpyruvate transaminase |
| Reaction: |
L-glutamine + phenylpyruvate = 2-oxoglutaramate + L-phenylalanine |
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For diagram of reaction, click here and for mechanism, click here |
| Other name(s): |
glutamine transaminase K; glutamine-phenylpyruvate aminotransferase |
| Systematic name: |
L-glutamine:phenylpyruvate aminotransferase |
| Comments: |
A pyridoxal-phosphate protein. L-Methionine, L-histidine and L-tyrosine can act as donors. The enzyme has little activity on pyruvate and glyoxylate (cf. EC 2.6.1.15 glutamine—pyruvate transaminase). |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 68518-06-9 |
| References: |
| 1. |
Cooper, A.J.L. Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and α-keto-γ-methiolbutyrate. Anal. Biochem. 89 (1978) 451–460. [DOI] [PMID: 727444] |
| 2. |
Cooper, A.J.L. and Meister, A. Isolation and properties of a new glutamine transaminase from rat kidney. J. Biol. Chem. 249 (1974) 2554–2561. [PMID: 4822504] |
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| [EC 2.6.1.64 created 1984] |
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