EC 2.6.1.26     
Accepted name: thyroid-hormone transaminase
Reaction: L-3,5,3′-triiodothyronine + 2-oxoglutarate = 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-2-oxopropanoate + L-glutamate
Other name(s): 3,5-dinitrotyrosine transaminase; thyroid hormone aminotransferase
Systematic name: L-3,5,3′-triiodothyronine:2-oxoglutarate aminotransferase
Comments: A pyridoxal-phosphate protein. Acts on monoiodotyrosine, diiodotyrosine, triiodothyronine, thyroxine and dinitrotyrosine (unlike EC 2.6.1.24 diiodotyrosine transaminase, which does not act on dinitrotyrosine). Pyruvate or oxaloacetate can act as acceptors.
References:
1.  Soffer, R.L., Hechtman, P. and Savage, M. L-Triiodothyronine aminotransferase. J. Biol. Chem. 248 (1973) 1224–1230. [PMID: 4686924]
[EC 2.6.1.26 created 1972]
 
 


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