The Enzyme Database

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Accepted name: riboflavin synthase
Reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
For diagram of riboflavin biosynthesis (late stages), click here
Other name(s): heavy riboflavin synthase; light riboflavin synthase; riboflavin synthetase; riboflavine synthase; riboflavine synthetase
Systematic name: 6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase
Comments: A flavoprotein (riboflavin).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9075-82-5
1.  Plaut, G.W.E. Studies on the nature of the enzymic conversion of 6,7-dimethyl-8-ribityllumazine to riboflavin. J. Biol. Chem. 238 (1963) 2225–2243. [PMID: 13944007]
2.  Plaut, G.W.E. and Harvey, R.A. Riboflavin synthetase. Methods Enzymol. 18B (1971) 527–538.
3.  Wacker, H., Harvey, R.A., Winestock, C.H. and Plaut, G.W.E. 4-(1′-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine, the second product of the riboflavin synthetase reaction. J. Biol. Chem. 239 (1964) 3493–3497. [PMID: 14245407]
[EC created 1972]

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