| EC |
2.5.1.9 |
| Accepted name: |
riboflavin synthase |
| Reaction: |
2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine |
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For diagram of riboflavin biosynthesis (late stages), click here |
| Other name(s): |
heavy riboflavin synthase; light riboflavin synthase; riboflavin synthetase; riboflavine synthase; riboflavine synthetase |
| Systematic name: |
6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase |
| Comments: |
A flavoprotein (riboflavin). |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9075-82-5 |
| References: |
| 1. |
Plaut, G.W.E. Studies on the nature of the enzymic conversion of 6,7-dimethyl-8-ribityllumazine to riboflavin. J. Biol. Chem. 238 (1963) 2225–2243. [PMID: 13944007] |
| 2. |
Plaut, G.W.E. and Harvey, R.A. Riboflavin synthetase. Methods Enzymol. 18B (1971) 527–538. |
| 3. |
Wacker, H., Harvey, R.A., Winestock, C.H. and Plaut, G.W.E. 4-(1′-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine, the second product of the riboflavin synthetase reaction. J. Biol. Chem. 239 (1964) 3493–3497. [PMID: 14245407] |
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| [EC 2.5.1.9 created 1972] |
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