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Your query returned 1 entry. 
Printable version
| EC | 2.5.1.126 | ||
| Accepted name: | norspermine synthase | ||
| Reaction: | S-adenosyl 3-(methylsulfanyl)propylamine + norspermidine = S-methyl-5′-thioadenosine + norspermine | ||
| Glossary: | norspermidine = bis(3-aminopropyl)amine norspermine = N,N′-bis(3-aminopropyl)-1,3-propanediamine spermidine = N-(3-aminopropyl)-1,4-butanediamine thermospermine = N-{3-[(3-aminopropyl)amino]propyl}-1,4-butanediamine |
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| Other name(s): | long-chain polyamine synthase (ambiguous) | ||
| Systematic name: | S-adenosyl 3-(methylsulfanyl)propylamine:norspermidine 3-aminopropyltransferase | ||
| Comments: | The enzyme, characterized from the thermophilic archaeon Pyrobaculum aerophilum, can also synthesize norspermidine from propane-1,3-diamine and thermospermine from spermidine (with lower activity). The long-chain polyamines stabilize double-stranded DNA at high temperatures. In contrast to EC 2.5.1.127, caldopentamine synthase, this enzyme does not accept norspermine as a substrate. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||
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