The Enzyme Database

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Accepted name: isoflavone 7-O-glucosyltransferase
Reaction: UDP-glucose + an isoflavone = UDP + an isoflavone 7-O-β-D-glucoside
For diagram of the biosynthesis of biochanin A, click here and for diagram of the biosynthesis of formononetin and derivatives, click here
Other name(s): uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDPglucose-favonoid 7-O-glucosyltransferase; UDPglucose:isoflavone 7-O-glucosyltransferase
Systematic name: UDP-glucose:isoflavone 7-O-β-D-glucosyltransferase
Comments: The 4′-methoxy isoflavones biochanin A and formononetin and, more slowly, the 4′-hydroxyisoflavones genistein and daidzein, can act as acceptors. The enzyme does not act on isoflavanones, flavones, flavanones, flavanols or coumarins.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 97089-62-8
1.  Köster, J. and Barz, W. UDP-glucose:isoflavone 7-O-glucosyltransferase from roots of chick pea (Cicer arietinum L.). Arch. Biochem. Biophys. 212 (1981) 98–104. [DOI] [PMID: 6458246]
[EC created 1989]

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