| EC |
2.3.1.320 |
| Accepted name: |
taxoid C-13 O-(3-amino-3-phenylpropanoyl)transferase |
| Reaction: |
baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = 3′-N-debenzoyl-2′-deoxytaxol + CoA |
| Glossary: |
(3R)-3-amino-3-phenylpropanoyl-CoA = (3R)-β-phenylalanyl-CoA |
| Other name(s): |
BAPT; baccatin III:3-amino-3-phenylpropanoyltransferase; baccatin III-3-amino-13-phenylpropanoyltransferase; 3′-N-de-benzoyl-2′-deoxytaxol-N-benzoyltransferase |
| Systematic name: |
(3R)-3-amino-3-phenylpropanoyl-CoA:baccatin III C-13 O-((3R)-3-amino-3-phenylpropanoyl)transferase |
| Comments: |
The enzyme is active in the biosynthetic pathway of paclitaxel (Taxol) in Taxus species (yew). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Walker, K., Fujisaki, S., Long, R. and Croteau, R. Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis. Proc. Natl. Acad. Sci. USA 99 (2002) 12715–12720. [DOI] [PMID: 12232048] |
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| [EC 2.3.1.320 created 2024] |
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