The Enzyme Database

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Accepted name: 2-acylglycerol O-acyltransferase
Reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol
Other name(s): acylglycerol palmitoyltransferase; monoglyceride acyltransferase; acyl coenzyme A-monoglyceride acyltransferase; monoacylglycerol acyltransferase
Systematic name: acyl-CoA:2-acylglycerol O-acyltransferase
Comments: Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9055-17-8
1.  Manganaro, F. and Kuksis, A. Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells. Can. J. Biochem. Cell Biol. 63 (1985) 341–347. [DOI] [PMID: 4016575]
[EC created 1972, modified 1986, modified 1989]

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