| EC |
2.3.1.167 |
| Accepted name: |
10-deacetylbaccatin III 10-O-acetyltransferase |
| Reaction: |
acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III |
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For diagram of taxol biosynthesis, click here |
| Systematic name: |
acetyl-CoA:taxan-10β-ol O-acetyltransferase |
| Comments: |
The enzyme will not acylate the hydroxy group at 1β, 7β or 13α of 10-deacetyl baccatin III, or at 5α of taxa-4(20),11-dien-5α-ol. May be identical to EC 2.3.1.163, 10-hydroxytaxane O-acetyltransferase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 220946-63-4 |
| References: |
| 1. |
Walker, K. and Croteau, R. Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli. Proc. Natl. Acad. Sci. USA 97 (2000) 583–587. [DOI] [PMID: 10639122] |
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| [EC 2.3.1.167 created 2002] |
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